Show simple item record

dc.contributor.authorWoodford, Timothy
dc.date.accessioned2015-09-24T19:41:15Z
dc.date.available2015-09-24T19:41:15Z
dc.identifier.urihttp://hdl.handle.net/10464/7244
dc.description.abstractThe production of 50 kHz ultrasonic vocalizations in rats has been associated with both positive social interactions and appetitive behavioural situations. Furthermore, there is significant evidence showing that these vocalizations are controlled by the meso-limbic dopamine system. The purpose of this study was to perform a pharmacological analysis of 50 kHz calls by using dopamine and two dopamine agonists amphetamine and apomorphine, to induce calls. The acoustic parameters of the different call types were compared across each agonist. All three agonists were able to significantly induce more 50 kHz vocalizations compared to the vehicle control. Furthermore, calls elicited by apomorphine had a significantly higher bandwidth compared to those elicited by dopamine and amphetamine. All three agonists also had significantly different pharmacokinetic properties. These observations suggest that the D2 receptor sub-type is involved in the length of call bandwidths.en_US
dc.language.isoengen_US
dc.publisherBrock Universityen_US
dc.subjectraten_US
dc.subject50 kHzen_US
dc.subjectultrasonic vocalizationen_US
dc.subjectdopamineen_US
dc.titlePharmacological analysis of 50 kHz vocalizations in the male raten_US
dc.typeElectronic Thesis or Dissertationen_US
dc.degree.nameM.Sc. Biological Sciencesen_US
dc.degree.levelMastersen_US
dc.contributor.departmentDepartment of Biological Sciencesen_US
dc.degree.disciplineFaculty of Mathematics and Scienceen_US
refterms.dateFOA2015-09-24T00:00:00Z


Files in this item

Thumbnail
Name:
Brock_Woodford_Tim_2015.pdf
Size:
930.9Kb
Format:
PDF
Description:
Main article

This item appears in the following Collection(s)

Show simple item record