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dc.contributor.authorAshish, Naveen
dc.contributor.authorBamman, Marcas
dc.contributor.authorCerny, Frank
dc.contributor.authorCooper, Dan
dc.contributor.authord'Memecourt, Pierre
dc.contributor.authorEisenmann, Joey
dc.contributor.authorEricson, Dawn
dc.contributor.authorFahey, John
dc.contributor.authorFalk, Bareket
dc.contributor.authorGabriel, Davera
dc.contributor.authorKahn, Michael
dc.contributor.authorKemper, Han
dc.contributor.authorLeu, Szu-Yun
dc.contributor.authorMcMurray, Robert
dc.contributor.authorNixon, Patricia
dc.contributor.authorOlin, J
dc.contributor.authorPianosi, Paolo
dc.contributor.authorPurucker, Mary
dc.contributor.authorRadom-Aizik, Shlomit
dc.contributor.authorTaylor, Amy
dc.date.accessioned2015-07-09T17:10:15Z
dc.date.available2015-07-09T17:10:15Z
dc.date.issued2015-02
dc.identifier.citation4. N. Ashish, M Bamman, FJ. Cerny, DM Cooper, P D’Hemecourt, JC. Eisenmann, DEricson, J Fahey, B Falk, D Gabriel, MG. Kahn, H C.G. Kemper, S-Y Leu, RI. Liem, R McMurray, PA. Nixon, JT Olin, PT. Pianosi, Mary Purucker, S Radom-Aizik, A Taylor (In Alphabetical order): The clinical translation gap in child health exercise research: A call for disruptive innovation. Clinical and Translational Science 2015 Feb;8(1):67-76. doi: 10.1111/cts.12194. [Epub ahead of print: 2014 Aug 11]en_US
dc.identifier.issn1752-8062
dc.identifier.urihttp://hdl.handle.net/10464/6945
dc.description.abstractIn children, levels of play, physical activity, and fitness are key indicators of health and disease and closely tied to optimal growth and development. Cardiopulmonary exercise testing (CPET) provides clinicians with biomarkers of disease and effectiveness of therapy, and researchers with novel insights into fundamental biological mechanisms reflecting an integrated physiological response that is hidden when the child is at rest. Yet the growth of clinical trials utilizing CPET in pediatrics remains stunted despite the current emphasis on preventative medicine and the growing recognition that therapies used in children should be clinically tested in children. There exists a translational gap between basic discovery and clinical application in this essential component of child health. To address this gap, the NIH provided funding through the Clinical and Translational Science Award (CTSA) program to convene a panel of experts. This report summarizes our major findings and outlines next steps necessary to enhance child health exercise medicine translational research. We present specific plans to bolster data interoperability, improve child health CPET reference values, stimulate formal training in exercise medicine for child health care professionals, and outline innovative approaches through which exercise medicine can become more accessible and advance therapeutics across the child health spectrum.en_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subjectExerciseen_US
dc.subjectClinical trialsen_US
dc.subjectPediatricsen_US
dc.subjectdata harmonizationen_US
dc.subjectcardiopulmonary exercise testingen_US
dc.titleThe Clinical Translation Gap in Child Health Exercise Research: A Call for Disruptive Innovationen_US
dc.typeArticleen_US


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