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    Inhibition of human lung cancer cell proliferation and survival by wine

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    Author
    Barron, Carly
    Moore, Jesse
    Tsakiridis, Theodoros
    Pickering, Gary
    Tsiani, Evangelia
    Keyword
    Cancer
    Proliferation
    Survival
    Proliferation
    Cancer
    
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    URI
    http://hdl.handle.net/10464/6138
    Abstract
    Compounds of plant origin and food components have attracted scientific attention for use as agents for cancer prevention and treatment. Wine contains polyphenols that were shown to have anti-cancer and other health benefits. The survival pathways of Akt and extracellular signal-regulated kinase (Erk), and the tumor suppressor p53 are key modulators of cancer cell growth and survival. In this study, we examined the effects of wine on proliferation and survival of human Non-small cell lung cancer (NSCLC) cells and its effects on signaling events.
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