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dc.contributor.authorMiotto, Paula
dc.date.accessioned2014-08-29T20:18:13Z
dc.date.available2014-08-29T20:18:13Z
dc.date.issued2014-08-29
dc.identifier.urihttp://hdl.handle.net/10464/5642
dc.description.abstractDirect high fat (HF) feeding has adverse effects on body composition and bone development in rodents. However, it is unclear whether maternal HF feeding has similar effects in male rat offspring. The objectives of this thesis were to determine if maternal HF feeding altered body composition, plasma hormones, bone development, and bone fatty acid composition in male offspring at weaning and 3 months of age. Maternal HF feeding increased bone mass and altered femur fatty acid composition at weaning, without differences in fat mass, lean mass, plasma hormones, or bone mass (femur or lumbar vertebrae). However, early differences did not persist at 3 months of age or contribute to lower bone strength – following consumption of a control diet post-weaning. These findings suggest that maternal HF feeding can alter body composition and bone development in weanling male offspring, without long-lasting effects if a healthy control diet is consumed post-weaning.en_US
dc.language.isoengen_US
dc.publisherBrock Universityen_US
dc.subjectNutritional programmingen_US
dc.subjectfatty aciden_US
dc.subjectbone developmenten_US
dc.subjecthigh fat dieten_US
dc.titleEffect of a high fat maternal diet on body composition and bone development in male offspringen_US
dc.typeElectronic Thesis or Dissertationen_US
dc.degree.nameM.Sc. Applied Health Sciencesen_US
dc.degree.levelMastersen_US
dc.contributor.departmentApplied Health Sciences Programen_US
dc.degree.disciplineFaculty of Applied Health Sciencesen_US
dc.embargo.termsNoneen_US
refterms.dateFOA2021-08-04T03:09:25Z


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