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Unique and unifying themes in the mechanisms regulating the expression of the arabidopsis thaliana PR-1 and Solanum tuberosum PR-10a inducible defense genes
(Brock University, 2010-10-25)
Arabidopsis is a model plant used to study disease resistance; Solanum tuberosum or
potato is a crop species. Both plants possess inducible defense mechanisms that are
deployed upon recognition ...
Mechanism of tocopherol transfer by human α-tocopherol transfer protein (α-hTTP)
(Brock University, 2010-10-26)
Vitamin E is a well known fat soluble chain breaking antioxidant. It is a general
tenn used to describe a family of eight stereoisomers of tocopherols. Selective retention
of a-tocopherol in the human circulation ...
Two enantiodivergent syntheses of balanol and the chemoenzymatic synthesis of oseltamivir
(Brock University, 2010-10-25)
The present thesis outlines our latest findings on the reactivity of the Burgess
reagent with oxiranes. Structural, mechanistic, and computational studies are
presented. Included is the development of a ...