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Saturation of SERCA's lipid annulus may protect against its thermal inactivation.

Fajardo, Val Andrew; Trojanowski, Natalie S.; Castelli, Laura; Miotto, Paula; Amoye, Foyinsola; Ward, Wendy E.; Tupling, A. Russell; LeBlanc, Paul (Elsevier, 2017-01-26)

The sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) pumps are integral membrane proteins that catalyze the active transport of Ca2+ into the sarcoplasmic reticulum, thereby eliciting muscle relaxation. SERCA pumps are ...