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Evaluation of neuropathological effects of a high-fat high-sucrose diet in middle-aged male C57BL6/J mice
(American Physiological Society, 2018-05-15)
Metabolic dysfunction related to diet-induced obesity has recently been linked to the pathogenesis of sporadic Alzheimer’s disease (AD). However, the underlying mechanisms linking obesity and AD remain unclear. The purpose ...
Acute exercise and brain BACE1 protein content: a time course study
(American Physiological Society, 2019-04-08)
Obesity and insulin resistance are risk factors in the development of neurodegenerative disorders. Previous work suggests that one acute bout of exercise may have beneficial neuro-protective effects in obese mice. The rate ...