Now showing items 1-4 of 4
Enantiodivergent chemoenzymatic synthesis of codeine
(Brock University, 2009-05-28)
The present thesis describes our latest results in the chemistry of morphine alkaloids. An enantiodivergent synthesis of codeine utilizing a cis-cyclohexadiene diol derived from microbial whole cell oxidation of ...
An exploratory study for the discovery of non-invasive hepatocellular carcinoma biomarkers among high-risk hepatitis C virus infected patients
(Brock University, 2009-01-28)
Hepatocellular Carcinoma (HCC) is a major healthcare problem, representing the third most common cause of cancer-related mortality worldwide. Chronic infections with Hepatitis B virus (HBV) and/or Hepatitis C virus (HCV) ...
The osmoadaptive response of the wine yeast Saccharomyces cerevisiae K1-V1116 during icewine fermentation
(Brock University, 2008-05-28)
The adapted metabolic response of commercial wine yeast under prolonged exposure to concentrated solutes present in Icewine juice is not fully understood. Presently, there is no information regarding the transcriptomic ...
The Elucidation of the involvement of endonuclease DNase y in reducing DNA transfection efficiency in mammalian cells
(Brock University, 2005-05-28)
Gene therapy is predicated upon efficient gene transfer. While viral vectors are the method of choice for transformation efficiency, the immunogenicity and safety concerns remain problematic. Non-viral vectors, on the ...