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dc.contributor.authorPaterson, Roger C.en_US
dc.date.accessioned2009-07-09T17:31:06Z
dc.date.available2009-07-09T17:31:06Z
dc.date.issued1984-07-09T17:31:06Z
dc.identifier.urihttp://hdl.handle.net/10464/1724
dc.description.abstractA strain of Drosophila melanogaster (mid america stock culture no. hl16) has been reported to be deficient in aldehyde oxidase activity (Hickey and Singh 1982). This strain was characterized during the course of this study and compared to other mutant strains known to be deficient in aldehyde oxidase activity. During the course of this investigation, the hl16 strain was found to be temperature sensitive in its viability. It was found that the two phenotypes, the enzyme deficiency, and the temperature sensitive lethality were the result of two different mutations, both mapping to the X-chromosome. These two mutations were found to be separable by recombination. The enzyme deficiency was found to map to the same locus as the cinnamon mutation, another mutation which affects aldehyde oxidase production. The developmental profile of aldehyde oxidase in the hl16 strain was compared to the developmental profile in the Canton S wild type strain. The aldehyde oxidase activity in adult hl16 individuals was also compared to that of various other strains. It was also found that the aldehyde oxidase activity was temperature sensitive in the adult flies. The temperature sensitive lethality mutation was mapped to position 1-0.1.en_US
dc.language.isoengen_US
dc.publisherBrock Universityen_US
dc.subjectDrosophila melanogaster.en_US
dc.subjectMutation (Biology)en_US
dc.subjectAldehydes.en_US
dc.subjectOxidases.en_US
dc.subjectTemperature--Physiological effect.en_US
dc.titleAnalysis of a temperature sensitive mutation affecting aldehyde oxidase activity in Drosophila melanogasteren_US
dc.typeElectronic Thesis or Dissertationen_US
dc.degree.nameM.Sc. Biological Sciencesen_US
dc.degree.levelMastersen_US
dc.contributor.departmentDepartment of Biological Sciencesen_US
dc.degree.disciplineFaculty of Mathematics and Scienceen_US
refterms.dateFOA2021-08-07T01:55:39Z


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