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Mechanisms underlying Retinoic acid-induced chemoattraction in molluscan neurons
(Brock University, 2010-10-25)
Retinoic acid, a derivative of vitamin A, is known to play diverse roles in development
and regeneration. Previous research in the mollusc Lymnaea stagnalis has shown that a
gradient of all-trans retinoic acid ...
Effects of low doses of quinpirole on production of 50 kHz vocalizations in Wistar rats
(Brock University, 2011-03-08)
Rats emit two distinct types of ultrasonic vocalizations in adulthood: 22 kHz (aversive
situation), and 50 kHz calls (appetitive situation). The present project is focussed on
pharmacological studies of ...
Characterizing the impact of multiple potential enemies (predators and parasites) on the behaviour of ranid tadpoles
(Brock University, 2010-10-26)
In order to fully understand an organism's behaviours the interactions between
multiple enemies or selective pressures need to be considered, as these interactions are
usually far more complex than the simple addition ...
The Implications of Forager Behaviour for Social Organisation in a Socially Polymorphic Carpenter Bee (Xylocopa virginica)
(2013-04-01)
In social Hymenoptera, the division of labour is a major step in the evolution of
sociality. Bees, which express many different kinds of sociality, can be classified
according to how individuals share or do not share ...
Elucidation of the Retinoid Signalling Pathway Involved in Axon Guidance in Lymnaea stagnalis and Xenopus laevis
(Brock University, 2012-11-07)
The vitamin A metabolite, retinoic acid (RA), is known to play a crucial role in several developmental processes including axial patterning and differentiation. More recently, RA has been implicated in the regenerative ...
Interactions between the cholinergic and dopaminergic systems during the production of ultrasonic vocalizations in rats
(Brock University, 2012-09-18)
Rats produce ultrasonic vocalizations that can be categorized into two types of ultrasonic calls based on their sonographic structure. One group contains 22-kHz ultrasonic vocalization (USVs), characterized by relatively ...
Interactions between the cholinergic and dopaminergic system during the production of ultrasonic vocalizations in rats
(Brock University, 2012-10-11)
Rats produce ultrasonic vocalizations that can be categorized into two types of ultrasonic calls based on their sonographic structure. One group contains 22-kHz ultrasonic vocalization (USVs), characterized by relatively ...
Genetic Analysis of Taste in Homo Sapiens
(Brock University, 2013-03-06)
There are many known taste receptors specific to each taste attribute. This thesis examines the relationship between single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) in known taste and taste pathway ...
A Survey of hMLH1 mRNA Splicing Profiles in Human Cell Lines: Comparing Primary Cultured Fibroblasts Before and After Oxidative Stress and Transiently versus Stably Demethylated Colon Cancer Derived Cell Lines
(2013-04-15)
Most human genes undergo alternative splicing and loss of splicing fidelity is
associated with disease. Epigenetic silencing of hMLH 1 via promoter cytosine
methylation is causally linked to a subset of sporadic non-polyposis ...
Correlation of Protein Homeostasis With Maximum Lifespans in Endothermic Vertebrates
(2013-04-15)
Cellular stress resistance has been shown to be highly correlated with longevity.
However, the mechanisms conferring this stress resistance have yet to be identified.
Maintenance of protein homeostasis is a critical ...