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dc.contributor.authorLapinskaite, Ringaile
dc.date.accessioned2020-01-13T14:15:54Z
dc.date.available2020-01-13T14:15:54Z
dc.identifier.urihttp://hdl.handle.net/10464/14607
dc.description.abstractThis thesis describes the synthesis and derivatization of narciclasine and pancratistatin. A detailed description is given to the total formal synthesis of pancratistatin through a reductive transposition approach and the total and semi-syntheses of 2-epi-narciclasine and its discovery as a new natural product. The last part of this work focuses on the search for a divergent approach to access C-1 narciclasine and C-1-pancratistatin derivatives from natural narciclasine. Experimental and spectral data are provided for the new compounds.en_US
dc.language.isoengen_US
dc.publisherBrock Universityen_US
dc.subjectAmaryllidaceae, alkaloids, narciclasine, pancratistatinen_US
dc.titleSynthesis and Derivatization of Amaryllidaceae Constituents – Narciclasine and Pancratistatinen_US
dc.typeElectronic Thesis or Dissertationen_US
dc.degree.namePh.D. Chemistryen_US
dc.degree.levelDoctoralen_US
dc.contributor.departmentDepartment of Chemistryen_US
dc.degree.disciplineFaculty of Mathematics and Scienceen_US


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