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dc.contributor.authorEmberson, Kassandra
dc.date.accessioned2016-03-11T16:47:15Z
dc.date.available2016-03-11T16:47:15Z
dc.identifier.urihttp://hdl.handle.net/10464/8687
dc.description.abstractThis thesis describes the use of an L−proline-derived chiral auxiliary for diastereoselective lithiation and ligand synthesis. Such compounds have been utilized in the Metallinos research group previously for the synthesis of N−substituted planar chiral ferrocenes. The first project describes the use of this chiral auxiliary as a directing group for N−benzyl substitution, providing products in up to 10:1 diastereomeric ratio (dr). These derivatives may serve as chiral ylidene precursors to serve as ligands in transition metal catalysis. In addition, an N−substituted planar chiral ferrocene ylidene ligand derived from the same chiral auxiliary was used to prepare rhodium complexes that were explored as potential catalysts for asymmetric hydroformylation.en_US
dc.language.isoengen_US
dc.publisherBrock Universityen_US
dc.subjectylidene, chiral, chiral auxiliary, asymmetric, lithiationen_US
dc.titleA Bicyclic L-Proline Derived Chiral Auxiliary for Asymmetric Synthesisen_US
dc.typeElectronic Thesis or Dissertationen
dc.degree.nameM.Sc. Chemistryen_US
dc.degree.levelMastersen_US
dc.contributor.departmentDepartment of Chemistryen_US
dc.degree.disciplineFaculty of Mathematics and Scienceen_US
refterms.dateFOA2015-12-23T00:00:00Z


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