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dc.contributor.authorAkseer, Nasreen
dc.contributor.authorKish, Kimberly
dc.contributor.authorRigby, W Alan
dc.contributor.authorGreenway, Matthew
dc.contributor.authorKlentrou, Panagiota
dc.contributor.authorWilson, Philip M
dc.contributor.authorFalk, Bareket
dc.date.accessioned2015-06-17T18:18:51Z
dc.date.available2015-06-17T18:18:51Z
dc.date.issued2015
dc.identifier.issn1748-7161
dc.identifier.urihttp://hdl.handle.net/10464/6843
dc.description.abstractPurpose: Adolescent idiopathic scoliosis (AIS) is often associated with low bone mineral content and density (BMC, BMD). Bracing, used to manage spine curvature, may interfere with the growth-related BMC accrual, resulting in reduced bone strength into adulthood. The purpose of this study was to assess the effects of brace treatment on BMC in adult women, diagnosed with AIS and braced in early adolescence. Methods: Participants included women with AIS who: (i) underwent brace treatment (AIS-B, n = 15, 25.6 ± 5.8 yrs), (ii) underwent no treatment (AIS, n = 15, 24.0 ± 4.0 yrs), and (iii) a healthy comparison group (CON, n = 19, 23.5 ± 3.8 yrs). BMC and body composition were assessed using dual-energy X-ray absorptiometry. Differences between groups were examined using a oneway ANOVA or ANCOVA, as appropriate. Results: AIS-B underwent brace treatment 27.9 ± 21.6 months, for 18.0 ± 5.4 h/d. Femoral neck BMC was lower (p = 0.06) in AIS-B (4.54 ± 0.10 g) compared with AIS (4.89 ± 0.61 g) and CON (5.07 ± 0.58 g). Controlling for lean body mass, calcium and vitamin D daily intake, and strenuous physical activity, femoral neck BMC was statistically different (p = 0.02) between groups. A similar pattern was observed at other lower extremity sites (p < 0.05), but not in the spine or upper extremities. BMC and BMD did not correlate with duration of brace treatment, duration of daily brace wear, or overall physical activity. Conclusion: Young women with AIS, especially those who were treated with a brace, have significantly lower BMC in their lower limbs compared to women without AIS. However, the lack of a relationship between brace treatment duration during adolescence and BMC during young adulthood, suggests that the brace treatment is not the likely mechanism of the low BMC.en_US
dc.language.isoenen_US
dc.publisherBioMed Centralen_US
dc.subjectAdolescenceen_US
dc.subjectAdulthooden_US
dc.subjectBoneen_US
dc.subjectBraceen_US
dc.subjectDXAen_US
dc.subjectExerciseen_US
dc.subjectFemaleen_US
dc.subjectGrowthen_US
dc.subjectMaturationen_US
dc.subjectNutritionen_US
dc.subjectPhysical activityen_US
dc.titleDoes bracing affect bone health in women with adolescent idiopathic scoliosis?en_US
dc.typeArticleen_US


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