Show simple item record

dc.contributor.authorMorden, Alexandra K
dc.date.accessioned2013-10-11T20:08:12Z
dc.date.available2013-10-11T20:08:12Z
dc.date.issued2013-10-11
dc.identifier.urihttp://hdl.handle.net/10464/5064
dc.description.abstractCentral administration of orexin-A has been shown to activate autonomic arousal in rats, reliably inducing anxiety-like behaviours in the open field. To date, there has yet to be a study investigating the role of orexin-A in the communication of such negative affective state. In the current study, forty-six adult male rats were chronically cannulated and administered orexin-A into the medial preoptic area/anterior hypothalamic area to determine the effect of this neuropeptide on anxiety-like behaviour and the production of 22 kHz aversive ultrasonic vocalizations. It was found that intracerebral administration of orexin-A increased autonomic arousal as measured by a significant increase in fecal boli output, however orexin-A did not significantly affect locomotor activity or induce 22 kHz calling. These data suggest that orexin-A is involved in the regulation of the autonomic aspect of anxiety-like behaviour but not in the vocal communication of such negative affecten_US
dc.language.isoengen_US
dc.publisherBrock Universityen_US
dc.subjectOrexin-A; Anxiety-like behaviour; 22 kHz calls; Ultrasonic vocalizations; Raten_US
dc.titleThe Role of Orexin-A in Anxiety and the Emission of Ultrasonic Vocalizations in Ratsen_US
dc.typeElectronic Thesis or Dissertationen
dc.degree.nameM.A. Psychologyen_US
dc.degree.levelMastersen_US
dc.contributor.departmentDepartment of Psychologyen_US
dc.degree.disciplineFaculty of Social Sciencesen_US
dc.embargo.termsNoneen_US
refterms.dateFOA2021-08-03T02:16:11Z


Files in this item

Thumbnail
Name:
BROCK_MORDEN_ALEXANDRA_2013.pdf
Size:
1.008Mb
Format:
PDF
Description:
MA Thesis Brock Morden, Alexandra

This item appears in the following Collection(s)

Show simple item record