Browsing Brock Theses by Subject "Genetic vectors."

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Development of a bovine adenovirus type 2-based gene delivery vector /

Ojkic, Davor. (Brock University, 1997-05-21)

ABSTRACT Recombinant adenoviruses are currently under intense investigation as potential gene delivery and gene expression vectors with applications in human and veterinary medicine. As part of our efforts to develop a ...
Development of packaging cell lines for rescuing BAV2 viral vectors

SalamÃ©, Mohamad S. (Brock University, 1999-07-09)

The construction of adenovirus vectors for cloning and foreign gene expression requires packaging cell lines that can complement missing viral functions caused by sequence deletions and/or replacement with foreign DNA ...
The Elucidation of the involvement of endonuclease DNase y in reducing DNA transfection efficiency in mammalian cells

Centre for Biotechnology (Brock University, 2005-05-28)

Gene therapy is predicated upon efficient gene transfer. While viral vectors are the method of choice for transformation efficiency, the immunogenicity and safety concerns remain problematic. Non-viral vectors, on the ...

Now showing items 1-3 of 3

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