Now showing items 1-3 of 3
Isolation, Synthesis, and Semi-synthesis of Amaryllidaceae Constituents from Narcissus and Galanthus sp.: De novo Total Synthesis of 2-epi-Narciclasine.
An efficient protocol for the isolation of narciclasine from common Amaryllidaceae bulbs, separation from haemanthamine, and the occurrence of a trace alkaloid, 2-epi-narciclasine are reported. Attempts to convert natural ...
Chemoenzymatic Approach to Tetrodotoxin: Synthesis of Fukuyama’s, Alonso’s, and Sato’s Advanced Intermediates
The advanced intermediates in the syntheses of tetrodotoxin reported by Fukuyama, Alonso, and Sato were prepared. The key steps in the synthesis of the title compounds involved the toluene dioxygenase–mediated dihydroxylation ...
Chemoenzymatic Synthesis of the Antifungal Compound(–)-Pestynol by a Convergent, Sonogashira Construction of the Central Yne-Diene
A total synthesis of the fungal-derived natural prod-uct pestynol is reported via a convergent chemoenzymatic ap-proach from the readily available precursors geranyl bromide,ethyl acetoacetate, trimethylsilylacetylene, and ...