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dc.contributor.authorWakefield, Brent
dc.date.accessioned2017-12-20T18:42:28Z
dc.date.available2017-12-20T18:42:28Z
dc.identifier.urihttp://hdl.handle.net/10464/13156
dc.description.abstractThe current levels of vitamin D (vit D) and calcium (Ca) in the AIN93G diet may be higher than required to support healthy bone structure and bone mineral density (BMD) in rodent models. The study objectives were to determine if lower levels of vit D (400 and 100 IU/kg) and Ca (0.35, 0.3, or 0.25%) support healthy bone structure and BMD while maintaining intestinal integrity in weanling male CD-1 mice up to 4 months of age. Lowering the levels of vit D (400 IU/kg) and Ca (0.35%) had no effect on bone structure and BMD, and fecal albumin levels were not different among groups, however, differences were observed in measures of serum LPS among groups. Adjusting the level of vit D to 400 IU/kg and Ca to 0.35% may provide sufficient levels for healthy bone structure and BMD, however further analysis of intestinal integrity is required.en_US
dc.language.isoengen_US
dc.publisherBrock Universityen_US
dc.subjectAIN-93Gen_US
dc.subjectVitamin Den_US
dc.subjectCalciumen_US
dc.subjectBoneen_US
dc.subjectIntestineen_US
dc.titleEffect of altering dietary calcium and vitamin D in AIN93G diet on bone development in CD-1 male miceen_US
dc.typeElectronic Thesis or Dissertationen_US
dc.degree.nameM.Sc. Applied Health Sciencesen_US
dc.degree.levelMastersen_US
dc.contributor.departmentApplied Health Sciences Programen_US
dc.degree.disciplineFaculty of Applied Health Sciencesen_US


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